Everything you need to know about testosterone, backed by the latest research. We turn complex topics like diagnosis, dosing, delivery methods, and lab results into simple, practical insights. Understand TRT benefits and risks, maintain estradiol balance, and spot drug interactions - all grounded in evidence, not hype.
Accurate testosterone measurement in men requires a morning serum (blood) testosterone test using validated lab methods, confirmed on at least two separate days before diagnosing “low T.” Here’s how timing, test type (total vs free), and common at-home kits can skew results and lead you toward the wrong next step. “If you get testosterone testing ...
In men with confirmed testosterone deficiency, testosterone replacement can modestly increase metabolic rate over 6–12 months, largely by adding lean muscle (which raises basal metabolic rate) and reducing visceral fat. The biggest payoff shows up when strength training, protein intake, and sleep are dialed in—and men with normal levels usually see little metabolic benefit while ...
SHBG is a liver-made carrier protein that tightly binds roughly 70% of circulating testosterone, so higher SHBG can lower free (bioavailable) testosterone and cause “low T” symptoms even when total testosterone looks normal; adult men typically fall around 13.3–89.5 nmol/L. Understanding where your SHBG sits helps explain what your tissues can actually use—and why treatment ...
In men with obesity (BMI over 30) and low testosterone, combining semaglutide with testosterone therapy can promote fat loss while helping preserve lean muscle by reducing adipose-driven aromatase conversion of testosterone to estradiol and supporting anabolic metabolism. Instead of treating weight and hormones as separate problems, this paired approach targets the feedback loop where visceral ...
Wearables, lab panels, and health apps are turning midlife checkups into data streams. Here is how smarter report optimization in men can turn those numbers into better energy, libido, and long-term health. “Most men now have more health data than their doctors had 20 years ago. The real win is not more testing, but turning ...