Posts in Testosterone 101

Everything you need to know about testosterone, backed by the latest research. We turn complex topics like diagnosis, dosing, delivery methods, and lab results into simple, practical insights. Understand TRT benefits and risks, maintain estradiol balance, and spot drug interactions - all grounded in evidence, not hype.

Searching for perimenopause sudden weight gain? What midlife weight gain really means for men

Searching for perimenopause sudden weight gain? What midlife weight gain really means for men

Susan Carter, MD: Endocrinologist & Longevity expert avatar
Susan Carter, MD: Endocrinologist & Longevity expert
Dec 10, 2025 · 14 min read

Noticed midlife weight gain (even while reading about perimenopause)? What it really means for men. If you found this while googling “perimenopause sudden weight gain” for a partner — or just because that phrase is everywhere — but you are really worried about your own growing gut, you are not alone. Perimenopause is a life ...

How to measure testosterone accurately in men

How to measure testosterone accurately in men

Alexander Grant, MD, PhD: Urologist & Men’s health advocate avatar
Alexander Grant, MD, PhD: Urologist & Men’s health advocate
Dec 10, 2025 · 13 min read

If you want real answers about your energy, strength, or sex drive, you need to know exactly how to measure testosterone — and which tests are worth your time and money. “If you get testosterone testing wrong, everything that follows — from lifestyle changes to prescriptions — is built on sand. The goal is simple: ...

Does testosterone increase metabolism in men?

Does testosterone increase metabolism in men?

Susan Carter, MD: Endocrinologist & Longevity expert avatar
Susan Carter, MD: Endocrinologist & Longevity expert
Dec 09, 2025 · 11 min read

Many men hear that more testosterone means a faster metabolism and effortless fat loss. In reality, testosterone can nudge metabolism in the right direction for men with true deficiency, but the payoff depends heavily on muscle, movement, diet, and sleep. “In my clinic, testosterone is never a magic metabolism hack. In men who are genuinely ...

Sex hormone binding globulin and testosterone in men: what your SHBG levels really mean

Sex hormone binding globulin and testosterone in men: what your SHBG levels really mean

Alexander Grant, MD, PhD: Urologist & Men’s health advocate avatar
Alexander Grant, MD, PhD: Urologist & Men’s health advocate
Dec 09, 2025 · 13 min read

Sex hormone binding globulin is more than a lab extra – your SHBG levels help explain why you can feel low testosterone symptoms even when your “total T” looks fine on paper. “When guys see SHBG on their lab report they often skip past it, but that little number can tell us why a ‘normal’ ...

Semaglutide and testosterone: The science of combining therapies for men

Semaglutide and testosterone: The science of combining therapies for men

Alexander Grant, MD, PhD: Urologist & Men’s health advocate avatar
Alexander Grant, MD, PhD: Urologist & Men’s health advocate
Dec 08, 2025 · 10 min read

For men fighting the double burden of obesity and low testosterone, standard diet advice often fails. New research suggests that combining metabolic support with hormone optimization creates a synergy that protects muscle while burning fat. “Men often view their weight and their hormones as two separate problems to solve. In reality, they are deeply interconnected. ...

Christmas SaleCHRISTMAS SALE: $250 $139/MONTH. LIMITED TIME OFFER!