Testosterone 101 | Veedma's evidence-based men's health articles

Understanding testosterone replacement therapy side effects and management

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Aug 23, 2025 · 15 min read

In men with confirmed hypogonadism, testosterone replacement therapy can relieve symptoms but can also cause predictable side effects because added testosterone feeds back on the hypothalamic-pituitary-testicular axis and changes downstream markers like blood counts. Many guidelines use total testosterone below about 300 ng/dL on two separate morning tests, interpreted with symptoms and the lab’s reference ...

Unexpected effects of testosterone therapy you should know

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert

Aug 23, 2025 · 16 min read

Testosterone therapy can cause “unexpected” side effects beyond libido and muscle gains, including bone marrow driven rises in hemoglobin/hematocrit that can reach erythrocytosis when hematocrit exceeds ~54%, along with water retention, acne, mood changes, and reduced fertility. Here’s what to monitor, why these effects happen, and how to manage them safely with your clinician. “Testosterone ...

Choosing the best testosterone replacement therapy clinic for you

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Aug 08, 2025 · 15 min read

The best TRT clinic is one that confirms true hypogonadism with both symptoms and repeat labs (often a consistently low morning total testosterone, commonly around 300 ng/dL depending on the lab and assay, and/or low free testosterone on an appropriate test) and then matches the dose, delivery method, and monitoring plan to your health risks. ...

Testosterone replacement therapy risks: The ones men miss until a lab test catches them

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert

Aug 07, 2025 · 15 min read

Testosterone replacement therapy risks are manageable for many men with confirmed hypogonadism, but they are not trivial and they require structured monitoring. The most common problems build slowly, so the men who do best are the ones who treat TRT like a medical program, not a quick upgrade. “Testosterone therapy can be life changing for ...