Posts in Testosterone 101

Everything you need to know about testosterone, backed by the latest research. We turn complex topics like diagnosis, dosing, delivery methods, and lab results into simple, practical insights. Understand TRT benefits and risks, maintain estradiol balance, and spot drug interactions - all grounded in evidence, not hype.

Does TRT raise blood pressure? What the science says

Does TRT raise blood pressure? What the science says

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 15, 2025 · 10 min read

Testosterone therapy offers a lifeline for vitality and strength, but concerns about cardiovascular health remain common. Here is an evidence-based breakdown of how hormone therapy affects your heart, blood vessels, and long-term health. “Many men avoid treating low testosterone because they fear heart issues, yet low testosterone itself is a significant risk factor for heart ...

High estrogen on trt symptoms: what happens when your balance shifts

High estrogen on trt symptoms: what happens when your balance shifts

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 13, 2025 · 11 min read

Testosterone replacement therapy is designed to optimize male hormones, but it can accidentally tip the scale toward estrogen dominance. Here is how to spot the signs, understand the chemistry, and regain your edge. “Many men start TRT thinking only about raising testosterone numbers. But the male body is an ecosystem, not a gas tank. If ...

Does masturbating lower testosterone? The science behind the myths

Does masturbating lower testosterone? The science behind the myths

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 12, 2025 · 9 min read

For years, gym lore and online forums have claimed that ejaculation kills your gains. Here is what clinical research actually says about self-pleasure, hormone baselines, and your long-term health. “The body is not a battery that runs out of charge when you use it. Ejaculation does not drain your testosterone reserves. While there are momentary ...

What happens if we release sperm daily? What science says about testosterone, muscle, and men’s health

What happens if we release sperm daily? What science says about testosterone, muscle, and men’s health

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 11, 2025 · 13 min read

Wondering what happens if we release sperm daily? For most healthy men, frequent ejaculation is safe and does not drain testosterone, kill muscle gains, or wreck long-term health — but there are a few important exceptions you should know about. “For the average healthy man, ejaculating every day is more of a lifestyle choice than ...

How to lower hematocrit on trt safely and effectively

How to lower hematocrit on trt safely and effectively

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 11, 2025 · 10 min read

Testosterone therapy can optimize your life, but it often comes with a hidden cost: thicker blood. Here is the science behind high red blood cell counts and the specific steps you can take to manage it without sacrificing your progress. “We often see men panic when their hematocrit climbs, fearing they must stop therapy immediately. ...

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