Testosterone 101

Everything you need to know about testosterone, backed by the latest research. We turn complex topics like diagnosis, dosing, delivery methods, and lab results into simple, practical insights. Understand TRT benefits and risks, maintain estradiol balance, and spot drug interactions - all grounded in evidence, not hype.

Is your diet sabotaging your hormones? The science of testosterone killing foods

Is your diet sabotaging your hormones? The science of testosterone killing foods

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 03, 2025 · 16 min read

Testosterone typically declines about 1% per year after age 35, but a “Western” diet high in ultra-processed fried foods, sugar-sweetened drinks, and refined grains is linked to even lower levels by driving chronic inflammation, belly fat, and insulin resistance. Here’s what the research says to limit, what to watch for, and how to build meals ...

Hot flush in males: Why it happens and how to stop the heat

Hot flush in males: Why it happens and how to stop the heat

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 01, 2025 · 13 min read

Most male hot flushes are triggered by a drop in testosterone that narrows the hypothalamus’ thermoneutral “comfort zone,” causing sudden heat-dumping responses like flushing and sweating (rates reach 70%–80% on androgen-deprivation therapy). Here’s how to tell whether low testosterone, medications, or another hormone problem is driving yours—and which treatments actually work. “When a man tells ...

Why no morning wood happens and what it reveals about your vascular health

Why no morning wood happens and what it reveals about your vascular health

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 01, 2025 · 14 min read

Losing morning erections for many weeks often means nocturnal penile tumescence is being blunted by reduced penile blood flow, impaired nerve signaling, or poor sleep — and it can flag vascular problems even when testosterone is normal. Here’s how to interpret the change and when it should prompt a closer look at diabetes and cardiovascular ...

How long does it take for testosterone to work? A clinical timeline for results

How long does it take for testosterone to work? A clinical timeline for results

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Nov 29, 2025 · 13 min read

In clinical trials of TRT for hypogonadism, libido, energy, and mood often improve within about 3–6 weeks, while erection quality and muscle/fat changes typically take 12–16 weeks and bone benefits start around 6 months. Because different tissues respond on different timelines, this guide shows what to expect month by month — and how regular 3‑month ...

Bioidentical hormone replacement therapy for men: Science, safety, and real-world results

Bioidentical hormone replacement therapy for men: Science, safety, and real-world results

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Nov 28, 2025 · 14 min read

Most prescription testosterone replacement used in men is already “bioidentical” — the hormone molecule is chemically identical to what the testes produce, even as levels commonly decline about 1% per year after age 30–40. The real question is whether you have symptomatic, consistently low testosterone and how to dose and monitor therapy to restore a ...

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