XY Files Blog

Evidence-based articles on testosterone, men's health, fitness, longevity, and sexual health.

Best immunity boosting foods for men: What to eat to support your immune system year-round

Best immunity boosting foods for men: What to eat to support your immune system year-round

Susan Carter, MD avatar
Susan Carter, MD: Endocrinologist & Longevity Expert
Feb 13, 2026 · 13 min read

The best immunity boosting foods are the ones that reliably provide the micronutrients and bioactive compounds your immune cells use to build barriers, signal threats, and resolve inflammation. This guide breaks down the highest-impact foods and shows how men can turn them into a simple, repeatable “immunity plate” for work, travel, and training. Written by: ...

Keto diet and CGM: What your glucose level can look like and how to avoid reverse metabolic inflexibility

Keto diet and CGM: What your glucose level can look like and how to avoid reverse metabolic inflexibility

Susan Carter, MD avatar
Susan Carter, MD: Endocrinologist & Longevity Expert
Feb 07, 2026 · 12 min read

On a ketogenic diet, CGM traces usually show a lower, flatter 24-hour glucose curve, while an occasional high-carb meal can cause a higher peak and slower return to baseline because fat adaptation temporarily reduces rapid glucose disposal (“reverse metabolic inflexibility”) rather than proving true insulin resistance. Learn how to interpret trends despite interstitial fluid lag ...

Blueprint supplements for vascular health: What science shows

Blueprint supplements for vascular health: What science shows

Susan Carter, MD avatar
Susan Carter, MD: Endocrinologist & Longevity Expert
Jan 30, 2026 · 12 min read

Research does not show that the branded “Blueprint Stack” supplement bundle itself improves vascular health outcomes in men; any likely benefit comes from the Mediterranean-style foods in the routine and the cardiometabolic improvements they support. This men’s health-focused Blueprint protocol review explains what’s in the stack based on public descriptions of Bryan Johnson’s Blueprint protocol, ...

Inflammation and heart disease in men: What to test and what to do next

Inflammation and heart disease in men: What to test and what to do next

Susan Carter, MD avatar
Susan Carter, MD: Endocrinologist & Longevity Expert
Jan 28, 2026 · 11 min read

Chronic, low-grade inflammation is a proven risk factor for atherosclerotic heart disease, and simple blood tests can detect it before symptoms appear. If your cholesterol looks “fine” but your family history, waistline, or energy say otherwise, inflammation may be the missing piece in your heart risk assessment. “Think of cholesterol as the building material for ...

Building muscle after 40: The smarter plan for strength, recovery, and hormones

Building muscle after 40: The smarter plan for strength, recovery, and hormones

Bruno Rodriguez, DPT, CSCS avatar
Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Jan 26, 2026 · 11 min read

Yes, building muscle after 40 is absolutely possible for men, but you usually need a tighter plan for training, protein, recovery, and hormone health than you did at 25. The win is not “more grind.” It is better programming, better fuel, and better monitoring so you can keep progressing with fewer setbacks. “After 40, the ...

Bulking vs cutting for men: How to pick the right bulk vs cut plan and keep it healthy

Bulking vs cutting for men: How to pick the right bulk vs cut plan and keep it healthy

Bruno Rodriguez, DPT, CSCS avatar
Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Jan 26, 2026 · 12 min read

Bulking and cutting are two nutrition and training phases that help men gain muscle in a small calorie surplus or lose fat in a small calorie deficit while lifting to protect lean mass. The key is control, because the fastest bulk vs cut approach often backfires with extra fat gain, muscle loss, or a drop ...

Testosterone and the Dietary Guidelines for Americans: What men should actually do

Testosterone and the Dietary Guidelines for Americans: What men should actually do

Susan Carter, MD avatar
Susan Carter, MD: Endocrinologist & Longevity Expert
Jan 21, 2026 · 12 min read

The Dietary Guidelines for Americans (DGA) do not provide testosterone targets. Men can use the DGA to support a healthy body weight and cardiometabolic health, which can indirectly support testosterone, and should seek medical evaluation for persistent symptoms or repeatedly low morning labs. Here’s what diet can improve, what it can’t, and how to act ...

Brain fog in men: Best vitamins for brain fog and memory, plus supplements that actually help

Brain fog in men: Best vitamins for brain fog and memory, plus supplements that actually help

Jonathan Pierce, PhD avatar
Jonathan Pierce, PhD: Clinical Psychologist & Neuroscience Specialist
Jan 20, 2026 · 13 min read

The best vitamins for brain fog and memory are usually the nutrients you are deficient in, most often B vitamins, vitamin D, omega 3 fats, magnesium, and antioxidant nutrients. The smart play is to treat brain fog like a clue, get the right labs, then use targeted brain fog supplements instead of guessing. “In men, ...

At what age does a man stop ejaculating? Understanding the changes in your body

At what age does a man stop ejaculating? Understanding the changes in your body

Alexander Grant, MD, PhD avatar
Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Jan 19, 2026 · 12 min read

There is no specific age when a man stops ejaculating, and many men can ejaculate throughout life, though semen volume and the “force” of ejaculation often decline with age.[1] If ejaculation changes suddenly or stops completely, it is worth getting checked because the cause is often identifiable and treatable. “Most men don’t hit a birthday ...

Athlete biomarker testing for longevity: The lab numbers that keep men performing longer

Athlete biomarker testing for longevity: The lab numbers that keep men performing longer

Susan Carter, MD avatar
Susan Carter, MD: Endocrinologist & Longevity Expert
Jan 19, 2026 · 12 min read

For longevity-focused men who train, repeating key labs, especially HbA1c (a three month average of blood sugar) and ApoB (the number of atherogenic particles that can enter artery walls), can reveal early metabolic drift and cardiovascular risk before performance drops or disease shows up. Pair those with iron, inflammation, and hormone and recovery markers to ...

What muscles does cycling work? A physiologist’s guide to building power

What muscles does cycling work? A physiologist’s guide to building power

Bruno Rodriguez, DPT, CSCS avatar
Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Jan 18, 2026 · 12 min read

Cycling primarily works the quadriceps, gluteus maximus, hamstrings, and calves, while the core and hip and lower back stabilizers brace the pelvis to transfer force through a cyclical pedal stroke where the foot stays in contact with the pedal. If you only push down on the pedals, you can leave meaningful power untapped and increase ...

Weights or cardio first? How to sequence your workouts for muscle, endurance, and fat loss

Weights or cardio first? How to sequence your workouts for muscle, endurance, and fat loss

Bruno Rodriguez, DPT, CSCS avatar
Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Jan 17, 2026 · 12 min read

For most men training for strength, muscle, fat loss, or general fitness, do weights before cardio, and do cardio first only when endurance is your top goal. The reason is simple: whichever workout you do first usually gets your best energy, your best form, and your best results. “If you can only train once, put ...

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