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All the latest articles from our medical experts on testosterone, men's health, and longevity.

Unexpected effects of testosterone therapy you should know

Unexpected effects of testosterone therapy you should know

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Aug 23, 2025 · 16 min read

Testosterone therapy can cause “unexpected” side effects beyond libido and muscle gains, including bone marrow driven rises in hemoglobin/hematocrit that can reach erythrocytosis when hematocrit exceeds ~54%, along with water retention, acne, mood changes, and reduced fertility. Here’s what to monitor, why these effects happen, and how to manage them safely with your clinician. “Testosterone ...

Navigating testosterone replacement therapy costs: A simple guide

Navigating testosterone replacement therapy costs: A simple guide

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Aug 09, 2025 · 13 min read

TRT can cost roughly $30 to $200 per month for generic injections (plus supplies) or $50 to $600+ per month for gels and patches, while pellets often run about $600 to $1,200 per insertion every 3 to 6 months. Your total cost is driven mainly by medication type, required labs, follow-up visit model, and insurance ...

Understanding testosterone potential risks and benefits: A safer TRT roadmap for men

Understanding testosterone potential risks and benefits: A safer TRT roadmap for men

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Aug 09, 2025 · 14 min read

Understanding testosterone potential risks and benefits comes down to this: testosterone therapy is most useful and safest when a real deficiency is confirmed on repeat early morning labs and followed with ongoing monitoring. Done well, treatment can improve libido, mood, and body composition, but it can also suppress fertility and raise hematocrit, so the workup ...

Choosing the best testosterone replacement therapy clinic for you

Choosing the best testosterone replacement therapy clinic for you

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Aug 08, 2025 · 15 min read

The best TRT clinic is one that confirms true hypogonadism with both symptoms and repeat labs (often a consistently low morning total testosterone, commonly around 300 ng/dL depending on the lab and assay, and/or low free testosterone on an appropriate test) and then matches the dose, delivery method, and monitoring plan to your health risks. ...

How testosterone replacement therapy injections can boost your mood

How testosterone replacement therapy injections can boost your mood

Dr. Jonathan Pierce, PhD avatar
Dr. Jonathan Pierce, PhD: Clinical Psychologist & Neuroscience Specialist
Aug 08, 2025 · 13 min read

In men with symptomatic hypogonadism (total testosterone consistently below roughly 264 to 300 ng/dL, depending on the lab assay and reference range), testosterone injections that restore levels to the mid normal range can modestly improve mood and vitality by increasing androgen signaling in brain reward and emotional balance circuits. Here’s who’s most likely to benefit, ...

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