Lifestyle & longevity

Design daily habits that support hormonal balance and long-term vitality. Master sleep and circadian timing, eat for metabolic stability, and use micronutrients with purpose. Make informed choices about alcohol, nicotine, sauna, and cold exposure. We translate longevity research into clear, practical playbooks you can apply today.

What is biohacking? The science of optimizing male biology

What is biohacking? The science of optimizing male biology

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Jan 03, 2026 · 10 min read

Biohacking is a data-driven approach to improving physiology by measuring key biomarkers (such as glucose, cortisol, and testosterone), changing lifestyle or environmental inputs, and re-testing using a “measure, modify, measure” loop. Here’s how mechanisms like epigenetic regulation and hormesis can help counter modern stressors and extend healthspan. “Biohacking is often marketed as a shortcut, but ...

Can you build muscle in a deficit? The science of body recomposition

Can you build muscle in a deficit? The science of body recomposition

Dr. Bruno Rodriguez, DPT, CSCS avatar
Dr. Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Jan 02, 2026 · 10 min read

Building muscle in a calorie deficit is possible when the deficit is mild (about 200–300 calories below maintenance) and paired with high protein intake plus progressive resistance training, allowing stored body fat to help cover the energy cost of muscle protein synthesis through improved nutrient partitioning. The key is learning the physiological “rules” that let ...

Is the male midlife crisis real? The science behind the slump

Is the male midlife crisis real? The science behind the slump

Dr. Jonathan Pierce, PhD avatar
Dr. Jonathan Pierce, PhD: Clinical Psychologist & Neuroscience Specialist
Dec 31, 2025 · 9 min read

A male “midlife crisis” isn’t a DSM-5 diagnosis, but the midlife slump is real: large studies show life satisfaction typically bottoms out around ages 47–48, often colliding with age-related testosterone decline and peak life stress. Here’s what’s happening in the brain and body—and how to navigate the shift with a strategy, not willpower. “We often ...

Peptides vs TRT: Which therapy optimizes male performance and longevity?

Peptides vs TRT: Which therapy optimizes male performance and longevity?

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 31, 2025 · 10 min read

TRT best optimizes male performance when a man has clinically low testosterone (levels decline about 1% per year after age 30) because it replaces missing androgen directly, while growth-hormone secretagogue peptides target recovery and tissue repair by stimulating the pituitary to pulse more of its own HGH—so neither is universally “better” for longevity. Here’s how ...

Joe Rogan’s 2025 stack: Onnit creatine 5g, what science says

Joe Rogan’s 2025 stack: Onnit creatine 5g, what science says

Dr. Bruno Rodriguez, DPT, CSCS avatar
Dr. Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Dec 30, 2025 · 10 min read

Creatine monohydrate is the most consistently performance-boosting supplement in Rogan’s stack because it raises muscle phosphocreatine to regenerate ATP during high-intensity training, while most OTC “testosterone boosters” and trendy biohacks are largely hype without a true deficiency or prescription therapy. Rogan has also talked about keeping it simple with “5 grams” of creatine per day, ...

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