Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

How long does it take for testosterone to work? A clinical timeline for results

Nov 29, 2025 · 13 min read

In clinical trials of TRT for hypogonadism, libido, energy, and mood often improve within about 3–6 weeks, while erection quality and muscle/fat changes typically take 12–16 weeks and bone benefits start around 6 months. Because different tissues respond on different timelines, this guide shows what to expect month by month — and how regular 3‑month ...

Bioidentical hormone replacement therapy for men: Science, safety, and real-world results

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Nov 28, 2025 · 14 min read

Most prescription testosterone replacement used in men is already “bioidentical” — the hormone molecule is chemically identical to what the testes produce, even as levels commonly decline about 1% per year after age 30–40. The real question is whether you have symptomatic, consistently low testosterone and how to dose and monitor therapy to restore a ...

8 signs of healthy sperm every man should know

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Nov 25, 2025 · 15 min read

Because sperm cells make up only about 5–10% of semen, the most reliable “signs” of healthy sperm are stable semen color and consistency, a decent ejaculate volume, no pain or blood, and semen-analysis results that meet reference ranges for count, motility, and morphology. Since sperm production takes about 74 days, tracking noticeable changes can help ...

Can kale really help erections? What the science actually says

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Nov 24, 2025 · 11 min read

Kale isn’t a proven standalone treatment for erectile dysfunction, but its dietary nitrates and antioxidants can support endothelial nitric-oxide signaling—the pathway that relaxes penile blood vessels to allow engorgement. Because ED is often a vascular problem and affects up to 75% of men at some point, the bigger win is using a heart-healthy, Mediterranean-style eating ...

Fadogia agrestis and tongkat ali: What science really says about this testosterone stack

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Nov 20, 2025 · 9 min read

Human clinical trials show tongkat ali can modestly improve testosterone—likely by lowering cortisol and SHBG—while fadogia agrestis has little to no robust human evidence and an unresolved side‑effect profile based mostly on animal data. The stack targets the HPG axis from two angles (tongkat “releases the brakes,” fadogia aims to boost LH), but the gap ...