Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

How long does a honey pack stay in your system? The risks

Dec 06, 2025 · 14 min read

“Honey pack” sexual-enhancement sachets are supplement products that often contain undeclared PDE5 inhibitors (such as sildenafil or tadalafil), creating Viagra/Cialis-like blood-vessel relaxation and erection effects that can last roughly 4–36 hours. Because the dose is unknown, they can cause dangerous blood-pressure drops—especially in men with heart disease or anyone taking nitrates or other interacting medications—so ...

Rectal delivery systems: Understanding the clinical role of suppositories in men’s health

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Dec 05, 2025 · 12 min read

Rectal suppositories deliver medication through the highly vascular rectal mucosa, partially bypassing first‑pass liver metabolism so some drugs (such as anti‑inflammatories) can reach effective levels within 30–60 minutes while targeting pelvic tissues with fewer stomach side effects than oral pills. Here’s when they’re clinically useful for men (constipation, hemorrhoids, pelvic/prostate pain, even certain erectile treatments) ...

Does stress cause low testosterone in men? What science really shows

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Dec 05, 2025 · 14 min read

Chronic psychological stress is linked to lower morning testosterone in men, largely because sustained HPA-axis cortisol output can suppress hypothalamic–pituitary–gonadal (GnRH/LH) signaling and reduce testicular testosterone production. Here’s how to recognize the stress–low T feedback loop and what actually helps break it. “Stress and testosterone talk to each other all day long. Short bursts of ...

Semen retention meaning and the science behind the hype

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Dec 05, 2025 · 12 min read

Semen retention is deliberate abstinence from ejaculation, and research suggests it doesn’t produce a sustained testosterone boost—one study found a modest rise around day 7 of abstinence that drifted back toward baseline despite continued retention. Here’s what the evidence says about how “holding semen” affects hormones, mood, sex, and long‑term health. “Your body is not ...

Does testosterone cause hair loss? Separating hormonal fact from fiction

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Dec 04, 2025 · 10 min read

Testosterone itself isn’t the direct cause of male pattern hair loss; the issue arises when 5‑alpha reductase converts it into DHT, which miniaturizes genetically androgen‑sensitive scalp follicles even when total testosterone is normal. With androgenetic alopecia affecting roughly 30%–50% of men by age 50, the real question is whether your follicles are “wired” to overreact—and ...