
Episode 1: Facing the truth: My experience with testosterone replacement therapy side effects
January 19, 2026 · 10:42
Evidence-based look at TRT side effects and the monitoring steps needed to manage them safely.
Dr. Bruno Rodriguez designs strength and recovery programs for professional athletes and patients recovering from surgery. He focuses on building strength, mobility, and effective recovery while lowering injury risk. His goal is for men to achieve the best performance in the gym and in daily life.
We only record episodes on the topics readers care about most.

January 19, 2026 · 10:42
Evidence-based look at TRT side effects and the monitoring steps needed to manage them safely.
New to Dr. Bruno Rodriguez, DPT, CSCS's work? Start with these reader-favorite guides.


Men over 40 can still build muscle and strength, but anabolic resistance and slower tissue repair often extend recovery from heavy sessions to roughly 48–72 hours, meaning the hypertrophy stimulus has to be higher to meaningfully trigger muscle protein synthesis. Here’s how to adjust training volume and target 30–40 g of high‑quality protein (~3–4 g ...


Bulking and cutting work by deliberately shifting energy balance: a 250–500 calorie daily surplus supports muscle protein synthesis and hypertrophy, while a sustained calorie deficit drives fat oxidation but can increase muscle protein breakdown. The key to body recomposition is committing to one clear signal for 12–16 weeks—rather than chasing muscle gain and leanness at ...


Cycling primarily works the quadriceps, gluteus maximus, and hamstrings, while the core and hip–lower back stabilizers brace the pelvis to transfer force through a closed-kinetic-chain pedal stroke. If you only push down on the pedals you can leave “half your potential power” unused and increase knee load—here’s how biomechanics and bike fit help you recruit ...


For most men trying to build strength and muscle, do weights first and finish with cardio, because cardio-first increases fatigue and AMPK signaling (and can drain glycogen), which can reduce lifting volume and potentially blunt mTOR-driven hypertrophy. If endurance is your main goal or you’re splitting sessions across the week, the “best” order changes—here’s how ...


Measurable muscle atrophy typically doesn’t begin until about 2–3 weeks of complete inactivity, with the first 5–7 days off usually reflecting depleted glycogen and water rather than lost contractile tissue. The real risk window—and why immobilization (bed rest or a cast) changes the timeline—comes down to how quickly protein synthesis drops when mechanical tension disappears. ...