TRT side effects

Articles covering the potential side effects of testosterone replacement therapy (TRT), from acne, hair loss, and mood changes to blood pressure, hematocrit, and fertility impacts. Learn how to recognize issues early, interpret labs, and adjust lifestyle or protocols to stay safe while optimizing performance and well-being.

TRT side effects. Facts and myths.

TRT side effects. Facts and myths.

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Nov 14, 2025 · 13 min read

Testosterone replacement can change energy, mood, strength, and sex drive — but it also shifts blood, skin, fertility, and prostate health. Here is a clear, evidence-based guide to TRT side effects and how to manage them safely. “Most problems blamed on TRT are preventable. The real risk is starting testosterone in the wrong man, at ...

5 testosterone side effects you must be aware of

5 testosterone side effects you must be aware of

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Oct 14, 2025 · 15 min read

Testosterone replacement commonly causes a 2–5 mmHg rise in blood pressure, can thicken blood via erythrocytosis (hematocrit may climb to ≥54%), may suppress sperm production and fertility, can increase oily skin/acne, and can worsen obstructive sleep apnea. Tracking blood pressure, hematocrit, and symptoms from day one helps you and your clinician adjust dose or formulation ...

Testosterone replacement therapy costs: Factors and savings tips

Testosterone replacement therapy costs: Factors and savings tips

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Aug 26, 2025 · 14 min read

TRT commonly costs about $60–$150 per month for generic injections when insurance covers key components, but can run $400–$1,000 per month for branded gels or pellets when you’re paying out of pocket. The gap is driven by labs, visit fees, and drug delivery choice—and knowing where to trim (without skipping guideline basics like two low ...

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