Testosterone replacement therapy

Articles covering the basics of TRT, including who it’s for, how it works, common protocols, expected benefits, and potential side effects. Learn how to optimize hormones safely to improve energy, body composition, libido, and long-term health.

Bioidentical hormone replacement therapy for men: Science, safety, and real-world results

Bioidentical hormone replacement therapy for men: Science, safety, and real-world results

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Nov 28, 2025 · 14 min read

Most prescription testosterone replacement used in men is already “bioidentical” — the hormone molecule is chemically identical to what the testes produce, even as levels commonly decline about 1% per year after age 30–40. The real question is whether you have symptomatic, consistently low testosterone and how to dose and monitor therapy to restore a ...

TRT side effects. Facts and myths.

TRT side effects. Facts and myths.

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Nov 14, 2025 · 13 min read

Testosterone replacement can change energy, mood, strength, and sex drive — but it also shifts blood, skin, fertility, and prostate health. Here is a clear, evidence-based guide to TRT side effects and how to manage them safely. “Most problems blamed on TRT are preventable. The real risk is starting testosterone in the wrong man, at ...

5 testosterone side effects you must be aware of

5 testosterone side effects you must be aware of

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Oct 14, 2025 · 15 min read

Testosterone replacement commonly causes a 2–5 mmHg rise in blood pressure, can thicken blood via erythrocytosis (hematocrit may climb to ≥54%), may suppress sperm production and fertility, can increase oily skin/acne, and can worsen obstructive sleep apnea. Tracking blood pressure, hematocrit, and symptoms from day one helps you and your clinician adjust dose or formulation ...

Testosterone replacement therapy costs: Factors and savings tips

Testosterone replacement therapy costs: Factors and savings tips

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Aug 26, 2025 · 14 min read

TRT commonly costs about $60–$150 per month for generic injections when insurance covers key components, but can run $400–$1,000 per month for branded gels or pellets when you’re paying out of pocket. The gap is driven by labs, visit fees, and drug delivery choice—and knowing where to trim (without skipping guideline basics like two low ...

Special OfferLab panels included: $300/year free for all members