Testosterone replacement therapy

Everything you need to know about TRT, from understanding when it's medically appropriate to navigating protocols, dosages, and managing side effects. Learn how testosterone replacement therapy can restore energy, muscle mass, and overall quality of life in men with low testosterone.

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Joe Rogan’s Onnit creatine 5 g: What research says

Joe Rogan’s Onnit creatine 5 g: What research says

Dr. Bruno Rodriguez, DPT, CSCS avatar
Dr. Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Dec 30, 2025 · 13 min read

Creatine monohydrate is one of the best supported supplements for improving repeated high intensity exercise performance and increasing lean mass when paired with resistance training. If you are asking “what creatine does Joe Rogan use” or “what creatine does Joe Rogan take,” the consistent evidence-based answer is creatine monohydrate, typically taken as about 5 g ...

Can testosterone increase blood pressure? A practical guide to TRT and blood pressure for men

Can testosterone increase blood pressure? A practical guide to TRT and blood pressure for men

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 15, 2025 · 11 min read

Yes, testosterone can increase blood pressure in some men, but the average effect is usually small and the research is mixed. The bigger issue is identifying who is most likely to see a rise, then monitoring blood pressure and lab markers so treatment stays safe. “When men ask me whether testosterone replacement therapy and blood ...

Does testosterone increase metabolism in men?

Does testosterone increase metabolism in men?

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 09, 2025 · 13 min read

In men with confirmed testosterone deficiency, testosterone replacement can modestly increase metabolic rate over 6 to 12 months, largely by adding lean muscle (which raises basal metabolic rate) and reducing visceral fat. The biggest payoff shows up when strength training, protein intake, and sleep are dialed in, and men with normal levels usually see little ...

Semaglutide and testosterone: The science of combining therapies for men

Semaglutide and testosterone: The science of combining therapies for men

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 08, 2025 · 11 min read

In men with obesity (BMI over 30) and low testosterone, combining semaglutide with testosterone therapy can promote fat loss while helping preserve lean muscle by reducing adipose-driven aromatase conversion of testosterone to estradiol and supporting anabolic metabolism. Instead of treating weight and hormones as separate problems, this paired approach targets the feedback loop where visceral ...

Testosterone before and after: What men can realistically expect from TRT

Testosterone before and after: What men can realistically expect from TRT

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 04, 2025 · 14 min read

Testosterone before and after changes are real for many men with confirmed testosterone deficiency, most often showing up as better energy, libido, and body composition when treatment is correctly chosen and monitored. But “trt before and after” results vary widely, so the goal is not a miracle transformation, it is a measurable, medically supervised return ...

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