Blood test interpretation

Learn how to read and understand common lab markers that affect men’s health, performance, and hormone optimization—like total and free testosterone, estradiol, SHBG, lipids, CBC, CMP, A1C, thyroid, and inflammatory markers. This tag helps you spot what’s normal vs. concerning, know what to retest, and make smarter decisions about training, nutrition, supplements, and TRT with your clinician.

Sex hormone binding globulin and testosterone in men: What your SHBG levels really mean

Sex hormone binding globulin and testosterone in men: What your SHBG levels really mean

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 09, 2025 · 13 min read

SHBG is a liver-made carrier protein that tightly binds roughly 70% of circulating testosterone, so higher SHBG can lower free (bioavailable) testosterone and cause “low T” symptoms even when total testosterone looks normal; adult men typically fall around 13.3–89.5 nmol/L. Understanding where your SHBG sits helps explain what your tissues can actually use—and why treatment ...

Men’s biomarker reports: What BMI ‘normal’ band means

Men’s biomarker reports: What BMI ‘normal’ band means

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 07, 2025 · 13 min read

Wearables, lab panels, and health apps are turning midlife checkups into data streams. Here is how smarter report optimization in men can turn those numbers into better energy, libido, and long-term health. “Most men now have more health data than their doctors had 20 years ago. The real win is not more testing, but turning ...

Can low testosterone cause joint pain?

Can low testosterone cause joint pain?

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 06, 2025 · 13 min read

Low testosterone can contribute to joint pain by increasing chronic inflammation and weakening the muscle, bone, and cartilage support that stabilizes joints, and studies have linked low levels to about double the risk of developing osteoarthritis. If aching knees or stiff shoulders come with fatigue, lower libido, or shrinking strength, it’s worth seeing how hormones ...

Does stress cause low testosterone in men? What science really shows

Does stress cause low testosterone in men? What science really shows

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 05, 2025 · 14 min read

Chronic psychological stress is linked to lower morning testosterone in men, largely because sustained HPA-axis cortisol output can suppress hypothalamic–pituitary–gonadal (GnRH/LH) signaling and reduce testicular testosterone production. Here’s how to recognize the stress–low T feedback loop and what actually helps break it. “Stress and testosterone talk to each other all day long. Short bursts of ...

Essential biomarkers runners should track to run faster and avoid injury

Essential biomarkers runners should track to run faster and avoid injury

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 04, 2025 · 14 min read

Key biomarkers runners should track include iron status (ferritin, hemoglobin), vitamin D, key hormones (cortisol, testosterone), blood-sugar markers, and inflammation/recovery signals — and many clinicians flag ferritin below about 30–35 ng/mL as a red flag for depleted iron stores that can reduce oxygen delivery and performance. Here’s how to interpret the numbers, spot problems before ...

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