Mental health

Everything you need to know about how hormones shape mood, focus, and emotional balance. We explore anxiety, depression, ADHD, stress response, and cognitive performance through the lens of neuroscience and endocrinology. Learn how to stabilize cortisol, support healthy testosterone levels, and rebuild mental clarity.

How quickly does B12 shot work for energy and cognitive focus?

How quickly does B12 shot work for energy and cognitive focus?

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 01, 2025 · 13 min read

Vitamin B12 shots can quickly correct low B12 in people who cannot absorb pills, but the benefits, timing, and safe injection technique depend on your health, your dose, and exactly where and how the shot is given. “For the right patient, a B12 injection is like fixing a blocked fuel line. If you’ve been running ...

How long does it take for testosterone to work? A clinical timeline for results

How long does it take for testosterone to work? A clinical timeline for results

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Nov 29, 2025 · 13 min read

In clinical trials of TRT for hypogonadism, libido, energy, and mood often improve within about 3–6 weeks, while erection quality and muscle/fat changes typically take 12–16 weeks and bone benefits start around 6 months. Because different tissues respond on different timelines, this guide shows what to expect month by month — and how regular 3‑month ...

Andrew Huberman sleep cocktail: What it is, what works, and what to skip

Andrew Huberman sleep cocktail: What it is, what works, and what to skip

Dr. Jonathan Pierce, PhD avatar
Dr. Jonathan Pierce, PhD: Clinical Psychologist & Neuroscience Specialist
Nov 26, 2025 · 14 min read

The Andrew Huberman sleep cocktail has gone viral as a “science-based” way to fall asleep faster. Here is what each ingredient really does, what the research shows, and how to use it safely—if at all. “The Huberman sleep cocktail is basically a curated mix of familiar supplements. One or two of them can modestly help ...

Why do energy drinks make me tired instead of energized?

Why do energy drinks make me tired instead of energized?

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Nov 21, 2025 · 13 min read

Energy drinks can make you feel tired because caffeine temporarily blocks adenosine (the brain’s sleep-pressure signal) and then, as caffeine levels drop, adenosine “rebounds,” often intensified by a blood-sugar spike-and-crash and disrupted sleep. One large can may pack 150–300 mg of caffeine (with most adults advised to stay under ~400 mg/day), so timing, dose, and ...

How testosterone replacement therapy injections can boost your mood

How testosterone replacement therapy injections can boost your mood

Dr. Jonathan Pierce, PhD avatar
Dr. Jonathan Pierce, PhD: Clinical Psychologist & Neuroscience Specialist
Aug 08, 2025 · 12 min read

In men with symptomatic hypogonadism (total testosterone below about 350 ng/dL), testosterone injections that restore levels to the mid‑normal range can modestly improve mood and vitality by increasing androgen signaling in brain reward and emotional‑balance circuits. Here’s who’s most likely to benefit, how the shots release hormone over days, and why they’re not a cure‑all. ...

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