Why do energy drinks make me tired instead of energized?

Susan Carter, MD: Endocrinologist & Longevity expert avatar
Susan Carter, MD: Endocrinologist & Longevity expert
Published Nov 21, 2025 · Updated Nov 24, 2025 · 12 min read
Why do energy drinks make me tired instead of energized?
Photo by Yap on Unsplash

If you keep asking “why do energy drinks make me tired” after every can of Red Bull or Monster, the answer is rarely just “caffeine.” It is usually a mix of brain chemistry, blood sugar swings, sleep disruption, and how often you reach for those cans in the first place.

“When patients ask me ‘why do energy drinks make me tired,’ it is almost always a sign that their brain and hormones are already stressed. The drink gives a short jolt, then exposes how depleted the system really is.”

Susan Carter, MD

The relationship

It sounds backward. You chug an energy drink to power through work, a workout, or a late-night drive. Yet an hour or two later you feel sluggish, foggy, and maybe even sleepier than before. Many people now type “why do energy drinks make me tired” into search bars because their experience does not match the promise on the can.

The short answer is that energy drinks are engineered for a fast, intense rise in alertness. That spike is driven by caffeine, sugar, and other stimulants. The brain and body then push back to restore balance. Your nervous system, blood sugar, and fluid balance all swing in the opposite direction, and you feel a crash.[1]

Controlled studies show that typical energy drink doses improve attention and reaction time for a few hours, but they also increase heart rate, blood pressure, and can worsen later sleep quality, especially when used in the afternoon or evening.[1] For some people, that combination turns a short-term lift into net fatigue over the day.

How it works

To really answer “why do energy drinks make me tired,” it helps to break down what is inside the can and what each piece does to your brain and body.

1. Caffeine blocks adenosine, then the “crash” hits

Caffeine is a stimulant that blocks adenosine, a brain chemical that builds up during the day and makes you feel sleepy. Most 8-ounce energy drinks contain about 80 milligrams of caffeine, and larger cans can easily contain 150–300 milligrams or more.[1] The U.S. Food and Drug Administration suggests 400 milligrams per day as an upper safe limit for most healthy adults.

When caffeine blocks adenosine, nerve cells in the brain fire faster and you feel more alert. Later, as the caffeine wears off, that built-up adenosine finally binds to its receptors. The swing from “blocked” to “flooded” can feel like a heavy wave of tiredness, especially if you are sensitive to caffeine or you took a high dose at once.[2]

2. Sugar spikes, then crashes, drain your energy

Many popular energy drinks contain 20–40 grams of sugar per can. Sugar is a simple carbohydrate that raises blood glucose, your body’s main quick fuel. A rapid rise in blood sugar triggers a strong insulin response from the pancreas. Insulin is a hormone that moves sugar from your blood into your cells.[3]

After a big sugar hit, blood glucose can drop quickly, sometimes falling below your usual baseline. This “sugar crash” can cause fatigue, shakiness, irritability, and trouble concentrating.[3] One randomized trial found that high-sugar energy drinks improved alertness for about an hour but led to increased sleepiness and reduced mental performance 90 minutes to 2 hours afterward compared with sugar-free versions.

3. Dehydration and “hidden” fluid loss sap stamina

Dehydration means your body has lost more fluid than it has taken in. Even mild dehydration, as little as 1–2% of body weight, can reduce alertness, increase fatigue, and worsen headaches. Caffeine is a mild diuretic, which means it can increase urine production, especially in people who do not use it regularly.

Some energy drinks are also taken before or during workouts or long gaming sessions, when people may sweat more and forget to drink water. The combination of extra urine output and low water intake can leave you slightly dried out. Dehydration also lowers blood volume, which can make your heart work harder and make you feel more exhausted.

4. Sleep disruption adds “invisible” fatigue

Beyond the crash, regular energy drink use can quietly damage your sleep. Caffeine has a half-life of about 5 hours in most adults. That means if you drink 200 milligrams at 4 p.m., you may still have around 100 milligrams in your system at 9 p.m., and a meaningful amount at bedtime.

Studies in adolescents and adults link frequent energy drink use with shorter sleep duration, more insomnia symptoms, and daytime sleepiness.[4] Poor sleep then makes you more likely to reach for another can the next day. This vicious cycle is a key reason many people report that energy drinks make them tired over the long run, even if they feel a short buzz.

5. Hormone and stress effects may blunt natural energy

The stress response system relies on cortisol, a hormone made by your adrenal glands. Cortisol normally peaks in the morning and falls at night. Caffeine and other stimulants temporarily boost cortisol and adrenaline, especially in people who are not regular users.[2]

Over time, repeated spikes can contribute to a feeling of “wired but tired.” Your baseline stress level is higher, your sleep is lighter, and your natural morning energy signal gets blunted. Although the idea of “adrenal fatigue” is not well supported as a formal diagnosis, chronic stress and short sleep clearly disrupt cortisol rhythms and subjective energy levels.

Conditions linked to it

When someone keeps wondering “why do energy drinks make me tired,” it can sometimes reveal an underlying health issue. The drink is not causing the whole problem. It is exposing a system that was already under strain.

  • Underlying sleep disorders: Energy drinks are often used to push through sleep apnea, insomnia, or shift work. People with chronic sleep restriction may be more prone to big crashes after stimulants and may have worse judgment about dose and timing.
  • Anxiety and panic disorders: Caffeine can worsen anxiety, heart palpitations, and restlessness. The brain then pushes harder to calm things down, which can feel like sudden exhaustion once the surge wears off.[2]
  • Metabolic issues and insulin resistance: If your cells already respond poorly to insulin, repeated sugar spikes from energy drinks can increase fatigue and mental fogginess more than in people with normal glucose control.[3]
  • High caffeine tolerance or dependence: Heavy daily caffeine users often need more to feel an effect, and withdrawal between doses can cause fatigue, headaches, and low mood. This can make each energy drink feel less helpful and each crash feel worse.
  • Low baseline energy from other causes: Conditions like iron deficiency anemia, hypothyroidism, or low testosterone can all lower baseline energy. Meta-analyses suggest that symptomatic men with total testosterone below 350 ng/dL or free testosterone below 100 pg/mL are most likely to benefit from targeted treatment, not just more caffeine.

Limitations note: Most research on energy drinks and health conditions is observational, which can show associations but cannot always prove cause and effect. People who drink more energy drinks may also have different sleep patterns, diets, and stress levels than those who do not.

Symptoms and signals

Here are common patterns that suggest your body is not handling energy drinks well:

  • Feeling sleepy, heavy, or mentally foggy 1–3 hours after an energy drink
  • Needing more cans over time to get the same effect
  • Afternoon or evening use that leads to trouble falling asleep or staying asleep
  • Waking unrefreshed even after a full night in bed
  • Headaches, shakiness, or irritability as the drink wears off
  • Fast heart rate, palpitations, or a sense of “inner jitter” followed by exhaustion
  • Dry mouth, dark urine, or dizziness that hint at dehydration
  • Relying on “emergency” cans before work, workouts, or exams more days than not
  • Noticing worse crashes if you skip breakfast or drink on an empty stomach

If these patterns are familiar, the question “why do energy drinks make me tired” is really your body asking for a different strategy for energy.

What to do about it

Here is a simple 1–2–3 plan to troubleshoot why energy drinks make you tired and what to do instead.

  1. Step 1: Get a clear picture of your current use and health

    • Track your intake for one week. Write down how many energy drinks you have, the brand, size, and time of day. Note how you feel 1–3 hours later.
    • Add up your total daily caffeine from all sources: energy drinks, coffee, tea, sodas, and pre-workout powders. Aim to stay at or below 400 milligrams per day if you are a healthy adult, and lower if you are sensitive or pregnant.
    • Log your sleep: what time you go to bed, how long it takes to fall asleep, how many times you wake, and how rested you feel in the morning.
    • Talk with a clinician if crashes are severe, if you have chest pain or intense anxiety, or if you suspect sleep apnea, depression, or hormonal issues.
  2. Step 2: Adjust how, when, and what you drink

    • Move the caffeine earlier. Try a “caffeine curfew” at least 6–8 hours before bedtime to protect sleep and reduce next-day fatigue.[4]
    • Cut sugar first. If you still want a boost, switch from high-sugar energy drinks to sugar-free versions or to coffee or tea with minimal added sugar to avoid sharp sugar crashes.
    • Hydrate in parallel. Drink at least one glass of water with each energy drink, and add another glass for every 30–60 minutes of hard exercise.
    • Eat real food with it. Pair any caffeine with a meal or snack that has protein, fiber, and healthy fats. This slows sugar absorption and smooths energy.
    • Test a taper. Reduce total caffeine by 50–100 milligrams every few days rather than quitting cold turkey to limit withdrawal fatigue and headaches.[2]
  3. Step 3: Build real energy from sleep, movement, and hormones

    • Protect 7–9 hours of sleep. Go to bed and wake up at consistent times, keep screens out of the bedroom, and make the room cool and dark.
    • Move daily. Even 10–20 minutes of brisk walking improves circulation, brain chemistry, and daytime alertness, reducing the need for artificial boosts.
    • Check the basics. If fatigue persists after improving caffeine habits, ask your clinician about checking blood counts, thyroid, iron, and, for men, testosterone levels using clear thresholds (total testosterone around or below 350 ng/dL or free testosterone below 100 pg/mL often signals a need for further evaluation).
    • Watch your mood. If you notice low mood, loss of interest, or anxiety along with your tiredness, screening for depression or anxiety is more useful than adding another can.

Myth vs Fact: Energy drinks and fatigue

  • Myth: “If I am tired after an energy drink, I just need a stronger one.”
    Fact: Feeling more tired is a sign your system is overshooting and crashing, not that you are “immune” to caffeine.
  • Myth: “Sugar-free energy drinks cannot make me crash because there is no sugar.”
    Fact: Sugar-free options avoid blood sugar swings, but the caffeine crash and sleep disruption can still leave you exhausted.
  • Myth: “I sleep fine even if I drink energy drinks at night, so they are not a problem.”
    Fact: Objective sleep studies show that caffeine fragments deep sleep even when you think you are sleeping “normally,” and that adds up to next-day fatigue.[4]
  • Myth: “Energy drinks are safe because they are sold everywhere.”
    Fact: Most healthy adults tolerate moderate use, but heavy or frequent intake, especially in teens and people with heart, sleep, or mental health issues, can cause real problems.[1]
  • Myth: “Feeling dependent on energy drinks is just a willpower issue.”
    Fact: Caffeine dependence and withdrawal are real, measurable phenomena, and breaking the cycle often needs a plan, not just “trying harder.”[2]

Bottom line

If you keep asking “why do energy drinks make me tired,” your body is giving you useful feedback. The mix of caffeine, sugar, dehydration, sleep disruption, and stress-hormone swings can turn a brief buzz into a longer slump, especially if your baseline sleep, metabolism, or hormones are already strained. Use that tired feeling as a signal to rethink not just what is in your can, but how you are sleeping, moving, eating, and managing stress. Energy drinks are a short-term tool at best. Real, sustainable energy comes from how well your system is tuned, not how hard you push the accelerator.

References

  1. Goldfarb M, Tellier C, Thanassoulis G. Review of published cases of adverse cardiovascular events after ingestion of energy drinks. The American journal of cardiology. 2014;113:168-72. PMID: 24176062
  2. Juliano LM, Griffiths RR. A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features. Psychopharmacology. 2004;176:1-29. PMID: 15448977
  3. Ludwig DS. The glycemic index: physiological mechanisms relating to obesity, diabetes, and cardiovascular disease. JAMA. 2002;287:2414-23. PMID: 11988062
  4. Watson EJ, Coates AM, Kohler M, et al. Caffeine Consumption and Sleep Quality in Australian Adults. Nutrients. 2016;8. PMID: 27527212

Get your FREE testosterone guide

Any treatment is a big decision. Get the facts first. Our Testosterone 101 guide helps you decide if treatment is right for you.

Susan Carter, MD: Endocrinologist & Longevity expert

Susan Carter, MD: Endocrinologist & Longevity expert

Dr. Susan Carter is an endocrinologist and longevity expert specializing in hormone balance, metabolism, and the aging process. She links low testosterone with thyroid and cortisol patterns and turns lab data into clear next steps. Patients appreciate her straightforward approach, preventive mindset, and calm, data driven care.

Black Friday SaleBLACK FRIDAY SALE: $250 $139/MONTH. LIMITED TIME OFFER!