Fertility & reproductive health

Navigate conception with clarity and science. Explore semen analysis, male infertility evaluations, and preparation for assisted reproduction like IVF and IUI. Learn how hCG, enclomiphene, and targeted supplements can improve sperm count, motility, and semen quality. Clear, evidence-based guidance to improve fertility and reproductive outcomes.

Enclomiphene: Double testosterone without injections

Enclomiphene: Double testosterone without injections

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Oct 12, 2025 · 12 min read

In randomized trials of men with functional hypogonadism, daily enclomiphene (a SERM) blocks estrogen feedback in the hypothalamus and pituitary to raise LH/FSH and increase morning testosterone into or near the normal range—sometimes roughly doubling very low baseline levels—while sperm counts stayed largely stable. Here’s who is most likely to benefit, what to monitor, and ...

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