TRT risks

Covers the potential downsides and side effects of testosterone replacement therapy (TRT), including cardiovascular concerns, fertility suppression, elevated hematocrit, estrogen-related issues, and prostate considerations. Learn how to evaluate risk factors, monitor labs, and make safer decisions to protect long-term health and performance.

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TRT side effects. Facts and myths.

TRT side effects. Facts and myths.

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Nov 14, 2025 · 13 min read

Testosterone replacement can change energy, mood, strength, and sex drive — but it also shifts blood, skin, fertility, and prostate health. Here is a clear, evidence-based guide to TRT side effects and how to manage them safely. “Most problems blamed on TRT are preventable. The real risk is starting testosterone in the wrong man, at ...

Unexpected effects of testosterone therapy you should know

Unexpected effects of testosterone therapy you should know

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Aug 23, 2025 · 15 min read

Testosterone therapy can cause “unexpected” side effects beyond libido and muscle gains, including bone-marrow–driven rises in hemoglobin/hematocrit that can reach erythrocytosis when hematocrit exceeds ~54%, along with water retention, acne, mood changes, and reduced fertility. Here’s what to monitor, why these effects happen, and how to manage them safely with your clinician. “Testosterone can be ...

Your guide to effective testosterone replacement therapy near me

Your guide to effective testosterone replacement therapy near me

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Aug 06, 2025 · 13 min read

Evidence-based testosterone replacement therapy is most likely to help men who have consistent low‑T symptoms plus a total testosterone below about 350 ng/dL (with free testosterone often under 100 pg/mL), confirmed with solid lab testing. Here’s how to tell whether testosterone is really the issue, what TRT can and can’t fix, and how to choose ...

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