Biological aging

Blueprint stack review: What Bryan Johnson’s simplified longevity stack can and can’t do for men

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert

Jan 30, 2026 · 11 min read

Bryan Johnson’s commercial “Blueprint Stack” promises a simplified route into a longevity-focused routine. This blueprint stack review breaks down what’s actually in the stack as described, what the research says about the major components for men, and how to use a “stack” approach without drifting into expensive guesswork. “If a ‘stack’ helps you consistently hit ...

Building muscle after 40: The science of getting stronger when recovery slows down

Dr. Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert

Jan 26, 2026 · 10 min read

Men over 40 can still build muscle and strength, but anabolic resistance and slower tissue repair often extend recovery from heavy sessions to roughly 48–72 hours, meaning the hypertrophy stimulus has to be higher to meaningfully trigger muscle protein synthesis. Here’s how to adjust training volume and target 30–40 g of high‑quality protein (~3–4 g ...

Athlete biomarker testing for longevity: The lab numbers that keep men performing longer

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert

Jan 19, 2026 · 11 min read

For longevity-focused men who train, repeating key labs—especially HbA1c (a ~3‑month average of blood sugar) and ApoB (the number of atherogenic particles that can enter artery walls)—can reveal early metabolic drift and cardiovascular risk before performance drops or disease shows up. Pair those with iron, inflammation, and hormone/recovery markers to build a “healthspan dashboard” that ...

The mitochondrial theory of aging: Why your cells lose power and how to fix it

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert

Jan 13, 2026 · 12 min read

Between ages 30 and 70, mitochondrial function in skeletal muscle can drop by 25–30%, lowering ATP production and slowing repair, fat metabolism, and hormone output—changes many researchers consider a core driver of aging. The good news is that mitochondria can respond to the right signals, and this guide shows how to recognize dysfunction and rebuild ...

What is biohacking? The science of optimizing male biology

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert

Jan 03, 2026 · 10 min read

Biohacking is a data-driven approach to improving physiology by measuring key biomarkers (such as glucose, cortisol, and testosterone), changing lifestyle or environmental inputs, and re-testing using a “measure, modify, measure” loop. Here’s how mechanisms like epigenetic regulation and hormesis can help counter modern stressors and extend healthspan. “Biohacking is often marketed as a shortcut, but ...

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Blueprint stack review: What Bryan Johnson’s simplified longevity stack can and can’t do for men

Building muscle after 40: The science of getting stronger when recovery slows down

Athlete biomarker testing for longevity: The lab numbers that keep men performing longer

The mitochondrial theory of aging: Why your cells lose power and how to fix it

What is biohacking? The science of optimizing male biology