Fitness & physical performance

Train with your hormones, not against them. We cover strength, hypertrophy, VO2 max, recovery, and injury prevention through an endocrine lens. Discover how training, nutrition, and daily activity can impact testosterone levels and support natural balance. Use estradiol balance for joint health, plan sleep taper cycles before competitions, and turn smart physiology into new PRs.

Essential biomarkers runners should track to run faster and avoid injury

Essential biomarkers runners should track to run faster and avoid injury

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 04, 2025 · 14 min read

Key biomarkers runners should track include iron status (ferritin, hemoglobin), vitamin D, key hormones (cortisol, testosterone), blood-sugar markers, and inflammation/recovery signals — and many clinicians flag ferritin below about 30–35 ng/mL as a red flag for depleted iron stores that can reduce oxygen delivery and performance. Here’s how to interpret the numbers, spot problems before ...

TRT before and after: What the clinical data actually promises for your body

TRT before and after: What the clinical data actually promises for your body

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 04, 2025 · 13 min read

In men with symptoms and consistently low testosterone (total testosterone under ~350 ng/dL, or free testosterone under ~100 pg/mL), TRT that restores levels to the mid‑normal range (~400–700 ng/dL) can increase lean muscle, reduce fat mass, and improve sexual function, with modest improvements in mood and vitality. The viral “before and after” transformations are often ...

FDA peptide regulations: What’s actually legal today

FDA peptide regulations: What’s actually legal today

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 03, 2025 · 9 min read

Peptides are legal in the U.S. only when they’re FDA‑approved drugs or can be compounded under Section 503A—however, the FDA’s “Category 2” list now includes 17 peptides (including BPC‑157) that pharmacies can no longer legally compound for human use. If you’re searching “FDA peptide regulation news today,” this Category 2 shift is the headline change ...

Do runners live longer? The science behind mileage and mortality

Do runners live longer? The science behind mileage and mortality

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 03, 2025 · 15 min read

In long-term studies, running as little as 5–10 minutes a day at an easy pace is linked to roughly a 3-year longer lifespan and about a 27% lower risk of all-cause mortality versus not running. The sweet spot for longevity appears to be moderate weekly volume (around 2–3 hours), not marathon-level mileage—here’s how it works ...

On Cloud X 3 review: The biomechanics of a true hybrid training shoe

On Cloud X 3 review: The biomechanics of a true hybrid training shoe

Dr. Bruno Rodriguez, DPT, CSCS avatar
Dr. Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Dec 02, 2025 · 10 min read

The Cloud X 3 functions as a true hybrid only for moderate lifting and short runs (about 1–4 miles) by pairing firmer, less-compressible CloudTec foam with a Speedboard to improve force transfer while still attenuating running impacts that can exceed 2.5× body weight. This evidence-based review breaks down where that stability–cushioning compromise works, where it ...

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