Fitness & physical performance

Train with your hormones, not against them. We cover strength, hypertrophy, VO2 max, recovery, and injury prevention through an endocrine lens. Discover how training, nutrition, and daily activity can impact testosterone levels and support natural balance. Use estradiol balance for joint health, plan sleep taper cycles before competitions, and turn smart physiology into new PRs.

Lifting in Converse: The biomechanics, benefits, and risks of flat sole training

Lifting in Converse: The biomechanics, benefits, and risks of flat sole training

Dr. Bruno Rodriguez, DPT, CSCS avatar
Dr. Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Dec 04, 2025 · 11 min read

Converse-style zero-drop, incompressible flat soles can improve center-of-pressure stability and reduce energy loss from sole compression in deadlifts, but for squats they remove the 0.75 to 1 inch heel lift that helps ankle dorsiflexion. If mobility is restricted, that can increase knee and lumbar torque. Here is how to know when flat shoes are the ...

Which essential biomarkers runners should track? The lab numbers that predict fatigue and low testosterone

Which essential biomarkers runners should track? The lab numbers that predict fatigue and low testosterone

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 04, 2025 · 15 min read

The essential biomarkers runners should track include vitamin D, iron and ferritin, magnesium and potassium, C reactive protein, testosterone, cortisol, blood glucose, and performance markers like VO2 max, lactate threshold, and resting heart rate. When those numbers drift, your training can feel harder, recovery slows, and injury risk rises even if your mileage looks “perfect.” ...

Testosterone before and after: What men can realistically expect from TRT

Testosterone before and after: What men can realistically expect from TRT

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 04, 2025 · 14 min read

Testosterone before and after changes are real for many men with confirmed testosterone deficiency, most often showing up as better energy, libido, and body composition when treatment is correctly chosen and monitored. But “trt before and after” results vary widely, so the goal is not a miracle transformation, it is a measurable, medically supervised return ...

BPC-157 FDA status in 2026: Compounding and legality

BPC-157 FDA status in 2026: Compounding and legality

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 03, 2025 · 13 min read

As of 2026, BPC-157, CJC-1295, and ipamorelin are not FDA-approved drugs, and all appear on the FDA’s Section 503A “Category 2” list (FDA Category 2 list, accessed February 15, 2026). Thymosin beta-4, which is often marketed online under the nickname “TB-500,” also appears on the FDA’s Section 503A “Category 2” list (FDA Category 2 list, ...

Do runners live longer? The science behind mileage and mortality

Do runners live longer? The science behind mileage and mortality

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 03, 2025 · 16 min read

In long-term studies, running as little as 5 to 10 minutes a day at an easy pace is linked to roughly a three-year longer lifespan and about a 27% lower risk of all-cause mortality versus not running. The sweet spot for longevity appears to be moderate weekly volume (around 2 to 3 hours), not marathon-level ...

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