Episode 1: Facing the truth: My experience with testosterone replacement therapy side effects
January 19, 2026 · 10:42
Evidence-based look at TRT side effects and the monitoring steps needed to manage them safely.
TRT monitoring
Covers how to track labs, symptoms, and side effects while on testosterone replacement therapy, including key blood markers like testosterone, estradiol, hematocrit, and lipids. Proper monitoring helps optimize results for energy, body composition, and performance while reducing health risks over the long term.
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TRT side effects. Facts and myths.
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Nov 14, 2025 · 13 min read
Testosterone replacement can change energy, mood, strength, and sex drive — but it also shifts blood, skin, fertility, and prostate health. Here is a clear, evidence-based guide to TRT side effects and how to manage them safely. “Most problems blamed on TRT are preventable. The real risk is starting testosterone in the wrong man, at ...
Facing the truth: My experience with testosterone replacement therapy side effects
Dr. Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Aug 06, 2025 · 12 min read
Testosterone replacement therapy can cause predictable side effects—most notably testosterone-driven increases in red blood cell production that push hematocrit above 54% in about 18–20% of men, a threshold linked to thicker blood and higher clot/cardiovascular risk when not monitored. Here’s how the main risks (blood, fluid retention, hair/skin changes, and hormone shutdown) happen and what ...