
Bioidentical hormone replacement therapy for men: Science, safety, and real-world results

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Nov 28, 2025 · 15 min read
Most prescription testosterone replacement used in men is already “bioidentical.” The hormone molecule is chemically identical to what the testes produce, even as levels commonly decline about 1% per year after age 30 to 40. The real question is whether you have symptomatic, consistently low testosterone and how to dose and monitor therapy to restore ...