TRT dosing and monitoring

Covers how to choose and adjust TRT doses and protocols, and which labs and symptoms to track over time. Learn how proper monitoring helps maximize benefits like energy, libido, and muscle while reducing risks such as high hematocrit, estradiol issues, or poor symptom control.

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The essentials for trt dosing and monitoring — then explore the latest posts below.

Bioidentical hormone replacement therapy for men: Science, safety, and real-world results

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Nov 28, 2025 · 14 min read

Most prescription testosterone replacement used in men is already “bioidentical” — the hormone molecule is chemically identical to what the testes produce, even as levels commonly decline about 1% per year after age 30–40. The real question is whether you have symptomatic, consistently low testosterone and how to dose and monitor therapy to restore a ...

What you need to know about testosterone replacement therapy risks

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert

Aug 07, 2025 · 14 min read

In men with confirmed hypogonadism (total testosterone below ~350 ng/dL or free testosterone below ~100 pg/mL), properly monitored TRT hasn’t shown a major rise in heart attack or stroke risk in recent trials, but it can increase hematocrit by stimulating red blood cell production and may worsen prostate symptoms or suppress fertility over time. Here’s ...