How testosterone replacement therapy injections can boost your mood
Dr. Jonathan Pierce, PhD: Clinical Psychologist & Neuroscience Specialist
Aug 08, 2025 · 12 min read
In men with symptomatic hypogonadism (total testosterone below about 350 ng/dL), testosterone injections that restore levels to the mid‑normal range can modestly improve mood and vitality by increasing androgen signaling in brain reward and emotional‑balance circuits. Here’s who’s most likely to benefit, how the shots release hormone over days, and why they’re not a cure‑all. ...