How testosterone replacement therapy injections can boost your mood
Dr. Jonathan Pierce, PhD: Clinical Psychologist & Neuroscience Specialist
Aug 08, 2025 · 13 min read
In men with symptomatic hypogonadism (total testosterone consistently below roughly 264 to 300 ng/dL, depending on the lab assay and reference range), testosterone injections that restore levels to the mid normal range can modestly improve mood and vitality by increasing androgen signaling in brain reward and emotional balance circuits. Here’s who’s most likely to benefit, ...