
Low libido: When the brain is the issue

Low libido in men is often a brain-and-life issue: changes in reward and stress signaling (including dopamine- and norepinephrine-driven “wanting”) can lower sexual desire for weeks or months even when testosterone is normal. About 15–25% of men report reduced desire at some point—here’s how mood, stress, medications, hormones, and daily habits interact, and what actually ...