PDE5 inhibitors

Covers PDE5 inhibitors like sildenafil and tadalafil, including how they support erectile function and blood flow, typical dosing strategies, and what to expect. Also explains side effects, contraindications (especially nitrates), and how they may fit into a men’s health plan alongside TRT, cardiovascular health, and performance goals.

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Erectile dysfanction in men: The causes doctors look for and a plan that works

Erectile dysfanction in men: The causes doctors look for and a plan that works

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Nov 01, 2025 · 15 min read

Erectile dysfunction is most often treatable, and in many men it is driven by blood flow problems, pelvic floor muscle issues, or a stress anxiety loop rather than “low testosterone” alone. The bigger point is that new erectile dysfunction can also be an early warning sign of cardiovascular risk, so a real workup is worth ...

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