Low testosterone and joint pain

Covers the connection between low testosterone and joint pain, stiffness, and inflammation, including why symptoms may show up alongside fatigue and reduced training performance. Learn what labs, lifestyle factors, and TRT-related considerations may help improve comfort, mobility, and recovery.

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Can low testosterone cause joint pain?

Can low testosterone cause joint pain?

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 06, 2025 · 13 min read

Low testosterone can contribute to joint pain by increasing chronic inflammation and weakening the muscle, bone, and cartilage support that stabilizes joints, and studies have linked low levels to about double the risk of developing osteoarthritis. If aching knees or stiff shoulders come with fatigue, lower libido, or shrinking strength, it’s worth seeing how hormones ...

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