Estrogen in men: Low Estradiol can ruin your TRT therapy
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Oct 26, 2025 · 13 min read
Low estradiol can derail TRT even when testosterone looks “normal,” because aromatase converts testosterone into estradiol and symptoms often appear when estradiol falls below about 20 pg/mL. Learn the key signs, the right lab test to order, and how to fix low E2 without crashing your hormones. “Men often think estrogen is the enemy, but ...