Longevity

How body fat speeds up aging in men: The science of metabolism and longevity

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert

Dec 10, 2025 · 14 min read

In men, excess visceral (deep belly) fat speeds up aging by acting as an inflammatory endocrine organ that releases cytokines such as TNF-α and IL-6, driving chronic inflammation, insulin resistance, and faster atherosclerosis. Losing just 5–10% of body weight in midlife can measurably improve blood sugar, blood pressure, and inflammatory markers—making fat loss one of ...

Metformin over the counter: Why it requires a script and how to get one safely

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert

Dec 08, 2025 · 11 min read

Metformin is prescription-only in the U.S., Canada, and the U.K. because it alters mitochondrial energy metabolism and relies on kidney clearance, so reduced renal function can increase the risk of lactic acidosis (dangerously high blood acidity). If you’re pursuing it for weight management or longevity, here’s how clinicians evaluate labs and prescribe it safely through ...

Low cost longevity tips that actually work, according to research

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert

Dec 02, 2025 · 13 min read

Research shows that a small set of low-cost habits—regular movement (about 7,000–8,000 steps per day), not smoking, a mostly whole-food diet, maintaining a healthy weight, and keeping alcohol low to moderate—are linked to roughly 10–14 more years of life and a lower risk of “all-cause mortality.” These “boring,” repeatable basics outperform most gadgets and supplements, ...

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How body fat speeds up aging in men: The science of metabolism and longevity

Metformin over the counter: Why it requires a script and how to get one safely

Low cost longevity tips that actually work, according to research