How body fat speeds up aging in men: The science of metabolism and longevity
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Dec 10, 2025 · 15 min read
In men, excess visceral (deep belly) fat speeds up aging by acting as an inflammatory endocrine organ that releases cytokines such as TNF-α and IL-6, driving chronic inflammation, insulin resistance, and faster atherosclerosis. Losing just 5 to 10% of body weight in midlife can measurably improve blood sugar, blood pressure, and inflammatory markers. This makes ...