Hormonal decline

Covers the gradual drop in key hormones—especially testosterone—that can occur with age, stress, poor sleep, and lifestyle factors. Learn how hormonal decline affects energy, libido, muscle, mood, and performance, and what testing and interventions can help.

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The essentials for hormonal decline — then explore the latest posts below.

Is the male midlife crisis real? The science behind the slump

Is the male midlife crisis real? The science behind the slump

Dr. Jonathan Pierce, PhD avatar
Dr. Jonathan Pierce, PhD: Clinical Psychologist & Neuroscience Specialist
Dec 31, 2025 · 9 min read

A male “midlife crisis” isn’t a DSM-5 diagnosis, but the midlife slump is real: large studies show life satisfaction typically bottoms out around ages 47–48, often colliding with age-related testosterone decline and peak life stress. Here’s what’s happening in the brain and body—and how to navigate the shift with a strategy, not willpower. “We often ...

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