Estrogen in men

Covers what estrogen does in the male body, how it affects libido, mood, body composition, and cardiovascular health, and why both low and high levels can cause problems. Learn common causes of imbalance, symptoms to watch for, and how to manage estrogen intelligently—especially during TRT.

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The essentials for estrogen in men — then explore the latest posts below.

Estrogen in men: Low Estradiol can ruin your TRT therapy

Estrogen in men: Low Estradiol can ruin your TRT therapy

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Oct 26, 2025 · 13 min read

Low estradiol can derail TRT even when testosterone looks “normal,” because aromatase converts testosterone into estradiol and symptoms often appear when estradiol falls below about 20 pg/mL. Learn the key signs, the right lab test to order, and how to fix low E2 without crashing your hormones. “Men often think estrogen is the enemy, but ...

Your guide to effective testosterone replacement therapy near me

Your guide to effective testosterone replacement therapy near me

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Aug 06, 2025 · 13 min read

Evidence-based testosterone replacement therapy is most likely to help men who have consistent low‑T symptoms plus a total testosterone below about 350 ng/dL (with free testosterone often under 100 pg/mL), confirmed with solid lab testing. Here’s how to tell whether testosterone is really the issue, what TRT can and can’t fix, and how to choose ...

Facing the truth: My experience with testosterone replacement therapy side effects

Facing the truth: My experience with testosterone replacement therapy side effects

Dr. Bruno Rodriguez, DPT, CSCS avatar
Dr. Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Aug 06, 2025 · 12 min read

Testosterone replacement therapy can cause predictable side effects—most notably testosterone-driven increases in red blood cell production that push hematocrit above 54% in about 18–20% of men, a threshold linked to thicker blood and higher clot/cardiovascular risk when not monitored. Here’s how the main risks (blood, fluid retention, hair/skin changes, and hormone shutdown) happen and what ...

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