High estrogen on trt symptoms: what happens when your balance shifts
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 13, 2025 · 11 min read
Testosterone replacement therapy is designed to optimize male hormones, but it can accidentally tip the scale toward estrogen dominance. Here is how to spot the signs, understand the chemistry, and regain your edge. “Many men start TRT thinking only about raising testosterone numbers. But the male body is an ecosystem, not a gas tank. If ...