
Enclomiphene: Double testosterone without injections

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Oct 12, 2025 · 13 min read
In randomized trials of men with functional hypogonadism, daily enclomiphene (a SERM) blocks estrogen feedback in the hypothalamus and pituitary to raise LH and FSH. This can increase morning testosterone into or near the normal range, and in some men with very low baseline levels it may roughly double testosterone on labs while sperm counts ...