Does Diet Coke break a fast?

Covers whether drinking Diet Coke (and other zero-calorie sweetened drinks) affects fasting goals like fat loss, insulin sensitivity, gut health, and autophagy. Useful for men using intermittent fasting to improve body composition, energy, and overall metabolic health.

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Does diet coke break a fast? What the science actually says

Does diet coke break a fast? What the science actually says

Dr. Susan Carter, MD avatar
Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Nov 29, 2025 · 14 min read

Diet Coke typically does not break a strict, calorie‑based fast because it contains about 0–5 calories per serving. But its non‑nutritive sweeteners can still activate sweet‑taste receptors and the gut–brain axis, potentially nudging insulin, gut hormones, and hunger—and quietly dulling some fasting benefits in certain people. “From a pure calorie standpoint, diet soda does not ...

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