Bioidentical hormones

Sex hormone binding globulin and testosterone in men: What your SHBG levels really mean

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Dec 09, 2025 · 13 min read

SHBG is a liver-made carrier protein that tightly binds roughly 70% of circulating testosterone, so higher SHBG can lower free (bioavailable) testosterone and cause “low T” symptoms even when total testosterone looks normal; adult men typically fall around 13.3–89.5 nmol/L. Understanding where your SHBG sits helps explain what your tissues can actually use—and why treatment ...

TRT before and after: What the clinical data actually promises for your body

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Dec 04, 2025 · 13 min read

In men with symptoms and consistently low testosterone (total testosterone under ~350 ng/dL, or free testosterone under ~100 pg/mL), TRT that restores levels to the mid‑normal range (~400–700 ng/dL) can increase lean muscle, reduce fat mass, and improve sexual function, with modest improvements in mood and vitality. The viral “before and after” transformations are often ...

Bioidentical hormone replacement therapy for men: Science, safety, and real-world results

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Nov 28, 2025 · 14 min read

Most prescription testosterone replacement used in men is already “bioidentical” — the hormone molecule is chemically identical to what the testes produce, even as levels commonly decline about 1% per year after age 30–40. The real question is whether you have symptomatic, consistently low testosterone and how to dose and monitor therapy to restore a ...

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Sex hormone binding globulin and testosterone in men: What your SHBG levels really mean

TRT before and after: What the clinical data actually promises for your body

Bioidentical hormone replacement therapy for men: Science, safety, and real-world results