
What is the difference between magnesium citrate and magnesium glycinate?

Dr. Susan Carter, MD: Endocrinologist & Longevity Expert
Nov 22, 2025 · 11 min read
Magnesium citrate is more likely to loosen stools and help constipation, while magnesium glycinate is typically better tolerated and is commonly used for sleep and daily supplementation. Here is the evidence-based breakdown of how citrate and glycinate affect your digestion, sleep, and absorption differently. “Patients often grab the first magnesium bottle they see, not realizing ...