Episode 1: Testosterone replacement therapy side effects: 7 risks
February 14, 2026 · 10:08
TRT has predictable, often preventable side effects: monitor testosterone, hematocrit, PSA, and blood pressure.
Aromatase
Learn about aromatase, the enzyme responsible for converting testosterone into estrogen, and its critical role in hormonal balance. Understanding aromatase activity is key for men managing TRT, optimizing testosterone levels, and controlling estrogen-related side effects.
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The essentials for aromatase — then explore the latest posts below.
What foods are high in estrogen? What high estrogen in men really means
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 24, 2025 · 11 min read
Many foods contain estrogen-like plant compounds, but typical servings rarely raise estrogen levels in men in a clinically meaningful way. The bigger drivers of high estrogen in men are often body fat, metabolic health, and environmental exposures, so the most effective fixes are usually not about “banning soy” or “quitting fruit.” “Most men who worry ...
Testosterone replacement therapy side effects: What men should watch and how to prevent the big ones
Dr. Bruno Rodriguez, DPT, CSCS: Strength, Recovery, and Physical Therapy Expert
Aug 06, 2025 · 13 min read
Testosterone replacement therapy side effects are usually predictable and often preventable when TRT is prescribed for true testosterone deficiency and monitored with routine labs. The biggest miss is treating TRT like a “set it and forget it” upgrade, instead of a medical plan with safety checkpoints. Key takeaways According to American Urological Association guidance, men ...