Androgen receptors

Explore how androgen receptors work, their role in mediating the effects of testosterone and other androgens, and why receptor sensitivity matters for muscle growth, hormonal health, and optimizing the results of TRT.

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The essentials for androgen receptors — then explore the latest posts below.

Does testosterone cause hair loss? Separating hormonal fact from fiction

Does testosterone cause hair loss? Separating hormonal fact from fiction

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Dec 04, 2025 · 11 min read

Testosterone itself isn’t the direct cause of male pattern hair loss; the issue arises when 5‑alpha reductase converts it into DHT, which miniaturizes genetically androgen‑sensitive scalp follicles even when total testosterone is normal. With androgenetic alopecia affecting roughly 30% to 50% of men by age 50, the real question is whether your follicles are “wired” ...

L carnitine benefits for men: What it can and cannot do for fat loss, workouts, and testosterone signaling

L carnitine benefits for men: What it can and cannot do for fat loss, workouts, and testosterone signaling

Dr. Alexander Grant, MD, PhD avatar
Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate
Oct 25, 2025 · 16 min read

L-carnitine can modestly improve endurance style training output and may support sperm motility in selected men, but it is not a guaranteed fat loss or testosterone shortcut. This evidence-based guide breaks down which l carnitine benefits are real, what dose and timeline matter, and how to use it like a structured experiment instead of a ...

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