Androgen deprivation therapy

Androgen deprivation therapy (ADT) is a medical treatment that lowers testosterone and other androgens, most commonly used in prostate cancer care. This topic covers how ADT affects muscle, strength, libido, mood, and metabolic health, and what men can do to support performance and long-term wellbeing during treatment.

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The essentials for androgen deprivation therapy — then explore the latest posts below.

9 foods that fight hot flashes: A tactical guide for men

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Jan 07, 2026 · 11 min read

In men with severe hypogonadism or on androgen deprivation therapy, hot flashes occur when falling testosterone disrupts the hypothalamic “set point,” triggering norepinephrine surges that drive rapid skin vasodilation and sweating—pathways diet can help calm by reducing neuro-inflammation and autonomic stress. If you’re among the up to 80% of men on ADT who experience these ...

Hot flush in males: Why it happens and how to stop the heat

Dr. Alexander Grant, MD, PhD: Urologist & Men's Health Advocate

Dec 01, 2025 · 13 min read

Most male hot flushes are triggered by a drop in testosterone that narrows the hypothalamus’ thermoneutral “comfort zone,” causing sudden heat-dumping responses like flushing and sweating (rates reach 70%–80% on androgen-deprivation therapy). Here’s how to tell whether low testosterone, medications, or another hormone problem is driving yours—and which treatments actually work. “When a man tells ...